Enables JUN kinase kinase activity; MAP-kinase scaffold activity; and protein kinase binding activity. Involved in several processes, including defense response to other organism; imaginal disc morphogenesis; and positive regulation of cellular component biogenesis. Located in axon. Is expressed in adult antennal lobe; adult brain; adult mushroom body; and organism. Used to study heart disease. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; lung carcinoma; and lung non-small cell carcinoma. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7).
FB Description
hemipterous (hep) encodes a serine/threonine protein kinase involved in the Jun-N-terminal kinase pathway by phosphorylating the product of bsk.