Gene

hep

Species
Drosophila melanogaster
Symbol
hep
Name
hemipterous
Synonyms
  • CG2190
  • CG4353
Biotype
protein coding gene
Automated Description
Enables JUN kinase kinase activity; MAP-kinase scaffold activity; and protein kinase binding activity. Involved in several processes, including defense response to other organism; imaginal disc morphogenesis; and positive regulation of cellular component biogenesis. Located in axon. Is expressed in adult antennal lobe; adult brain; adult mushroom body; and organism. Used to study heart disease. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; lung carcinoma; and lung non-small cell carcinoma. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7).
FB Description
hemipterous (hep) encodes a serine/threonine protein kinase involved in the Jun-N-terminal kinase pathway by phosphorylating the product of bsk.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47238
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
13.080M13.081M13.082M13.083M13.084M13.085M13.086M13.087M13.088M13.089M13.090M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions