Enables TBP-class protein binding activity and TFIID-class transcription factor complex binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in nucleus. Part of transcription factor TFIIA complex. Is expressed in organism. Orthologous to several human genes including GTF2A1 (general transcription factor IIA subunit 1).
FB Description
Transcription factor IIA L (TfIIA-L) encodes a precursor protein that, after proteolysis, produces the two larger subunits of TFIIA. TFIIA is a general transcription factor that is required for initiation by RNA polymerase II and is a component of the pre-initiation complex.