Gene

ksr

Species
Drosophila melanogaster
Symbol
ksr
Name
kinase suppressor of ras
Synonyms
  • CG2899
  • dKsr
Biotype
protein coding gene
Automated Description
Enables MAP-kinase scaffold activity; kinase binding activity; and protein kinase activator activity. Involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; open tracheal system development; and positive regulation of intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to several human genes including KSR1 (kinase suppressor of ras 1).
FB Description
kinase suppressor of ras (ksr) encodes a MAP-kinase scaffold protein. It mediates the activation of the serine/threonine kinase encoded by Dsor1.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23257
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.4785M5.4790M5.4795M5.4800M5.4805M5.4810M5.4815M5.4820M5.4825M5.4830M5.4835M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions