Gene

Rme-8

Species
Drosophila melanogaster
Symbol
Rme-8
Name
Receptor mediated endocytosis 8
Synonyms
  • CG8014
  • E(shi)2-1
Biotype
protein coding gene
Automated Description
Involved in positive regulation of border follicle cell migration and receptor-mediated endocytosis. Predicted to be active in endosome membrane. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic Malpighian tubule; embryonic/larval garland cell; and spermatozoon. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13).
FB Description
Receptor mediated endocytosis 8 (Rme-8) encodes a protein involved in the regulation of border follicle cell migration and the endocytosis of the receptor encoded by N.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR36983
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            9.168M9.169M9.170M9.171M9.172M9.173M9.174M9.175M9.176M9.177M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Rme-8 molecule type
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              Genetic Interactions

              Rme-8 role
              Rme-8 genetic perturbation
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