Gene

ND-75

Species
Drosophila melanogaster
Symbol
ND-75
Name
NADH dehydrogenase (ubiquinone) 75 kDa subunit
Synonyms
  • CG2286
  • dNDUFS1
Biotype
protein coding gene
Automated Description
Predicted to enable iron-sulfur cluster binding activity. Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in cellular respiration; mitochondrial respiratory chain complex I assembly; and reactive oxygen species metabolic process. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and ganglia. Used to study mitochondrial metabolism disease and nuclear type mitochondrial complex I deficiency 5. Human ortholog(s) of this gene implicated in inherited metabolic disorder; mitochondrial complex I deficiency; and nuclear type mitochondrial complex I deficiency 5. Orthologous to human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11615
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.2490M8.2495M8.2500M8.2505M8.2510M8.2515M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions