Gene

dve

Species
Drosophila melanogaster
Symbol
dve
Name
defective proventriculus
Synonyms
  • CG5799
  • compass
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including copper ion import; imaginal disc-derived appendage morphogenesis; and midgut development. Located in cytosol and nucleus. Is expressed in several structures, including embryonic/larval midgut cell; ganglia; gut section; head epidermis primordium; and imaginal disc. Human ortholog(s) of this gene implicated in SATB2-associated syndrome. Orthologous to human SATB1 (SATB homeobox 1) and SATB2 (SATB homeobox 2).
FB Description
defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15116
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
22.245M22.250M22.255M22.260M22.265M22.270M22.275M22.280M22.285M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions