Gene

Trxr1

Species
Drosophila melanogaster
Symbol
Trxr1
Name
Thioredoxin reductase 1
Synonyms
  • 2151
  • anon-WO03040301.185
Biotype
protein coding gene
Automated Description
Enables protein homodimerization activity and thioredoxin-disulfide reductase (NADPH) activity. Involved in cell redox homeostasis. Located in mitochondrion. Is expressed in adult brain; adult brain cell body rind; adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Orthologous to human TXNRD2 (thioredoxin reductase 2).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR48105
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.2430M8.2435M8.2440M8.2445M8.2450M8.2455M8.2460M8.2465M8.2470M8.2475M8.2480M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions