Gene

Sox100B

Species
Drosophila melanogaster
Symbol
Sox100B
Name
Sox100B
Synonyms
  • CG12098
  • CG15552
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in male gonad development. Predicted to be active in nucleus. Is expressed in several structures, including Malpighian tubule primordium; anal pad primordium; embryonic anal pad; gonad; and somatic cell of ovariole. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome (multiple); campomelic dysplasia; and lung cancer (multiple). Orthologous to several human genes including SOX10 (SRY-box transcription factor 10) and SOX9 (SRY-box transcription factor 9).
FB Description
Sox100B (Sox100B) encodes a group E Sox domain transcription factor. It has a role in the development of somatic components of the testis during metamorphosis, where it regulates pigment cell specification. Sox100B shows sexually dimorphic expression in the embryonic gonad.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45803
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
31.066M31.068M31.070M31.072M31.074M31.076M31.078M31.080M31.082M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions