Gene

DIP2

Species
Drosophila melanogaster
Symbol
DIP2
Name
DISCO Interacting Protein 2
Synonyms
  • CG7020
  • Ddip2
Biotype
protein coding gene
Automated Description
Predicted to enable acetate-CoA ligase activity. Involved in axon guidance. Located in plasma membrane. Is expressed in several structures, including adult head; ganglia; spermatozoon; and visceral trunk mesoderm. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human DIP2A (disco interacting protein 2 homolog A); DIP2B (disco interacting protein 2 homolog B); and DIP2C (disco interacting protein 2 homolog C).
FB Description
DISCO Interacting Protein 2 (DIP2) encodes a member of DIP2 family. It interacts physically with the product of disco in vitro and participates in axonal bifurcation and guidance downstream of the JNK pathway.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22754
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions