Predicted to enable acetate-CoA ligase activity. Involved in axon guidance. Located in plasma membrane. Is expressed in several structures, including adult head; ganglia; spermatozoon; and visceral trunk mesoderm. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human DIP2A (disco interacting protein 2 homolog A); DIP2B (disco interacting protein 2 homolog B); and DIP2C (disco interacting protein 2 homolog C).
FB Description
DISCO Interacting Protein 2 (DIP2) encodes a member of DIP2 family. It interacts physically with the product of disco in vitro and participates in axonal bifurcation and guidance downstream of the JNK pathway.