Gene

eIF3e

Species
Drosophila melanogaster
Symbol
eIF3e
Name
eukaryotic translation initiation factor 3 subunit e
Synonyms
  • BcDNA:GM01233
  • BcDNA.GM01233
Biotype
protein coding gene
Automated Description
Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Located in intracellular membrane-bounded organelle. Is expressed in several structures, including adult head; adult heart; anterior endoderm; embryonic/larval midgut primordium; and ganglia. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E).
FB Description
eukaryotic translation initiation factor 3 subunit e (eIF3e) encodes a component of the translation initiation complex and is a positive regulator of cullin neddylation, which is required for Cullin-ring ubiquitin ligase activity. It also regulates spindle assembly, microtubule dynamics and mitotic progression.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10317
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            16.7854M16.7856M16.7858M16.7860M16.7862M16.7864M16.7866M16.7868M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            eIF3e molecule type
            Interactor gene
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              Genetic Interactions

              eIF3e role
              eIF3e genetic perturbation
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