Version: 8.0.0
Date: Tue Jan 28 2025
AkhR
Drosophila melanogasterFB:FBgn0025595
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

AkhR

Species
Drosophila melanogaster
Symbol
AkhR
Name
Adipokinetic hormone receptor
Synonyms
  • adipokinetic hormone receptor
  • Adipokinetic Hormone Receptor
Biotype
protein coding gene
Automated Description
Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Involved in several processes, including cellular response to starvation; glucose homeostasis; and triglyceride homeostasis. Located in membrane. Is expressed in adult fat body; adult head; adult subesophageal zone; embryonic/larval fat body; and gustatory receptor neurons. Used to study obesity. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia. Orthologous to several human genes including GNRHR (gonadotropin releasing hormone receptor).
FB Description
Adipokinetic hormone receptor (AkhR) encodes a G protein-coupled receptor for the hormone encoded by Akh. It modulates both lipid and carbohydrate homeostasis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24241
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

          Model name
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          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
            Viewer Help
            6.7115M6.7120M6.7125M6.7130M6.7135M6.7140M6.7145M6.7150M6.7155M6.7160M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            AkhR molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              AkhR role
              AkhR genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
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