Gene

Mcm6

Species
Drosophila melanogaster
Symbol
Mcm6
Name
Minichromosome maintenance 6
Synonyms
  • CG4039
  • dMcm6
Biotype
protein coding gene
Automated Description
Contributes to 3'-5' DNA helicase activity. Involved in DNA replication and eggshell chorion gene amplification. Located in nucleus. Part of CMG complex and MCM complex. Is expressed in presumptive embryonic/larval central nervous system and unfertilized egg. Orthologous to human MCM6 (minichromosome maintenance complex component 6).
FB Description
Minichromosome maintenance 6 (Mcm6) encodes a subunit of the hetero-hexameric mini-chromosome maintenance (MCM) Complex, which is the eukaryotic replicative DNA helicase. MCM complex requires association with CDC45L and the GINS complex for full helicase activity.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11630
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.6745M6.6750M6.6755M6.6760M6.6765M6.6770M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions