Contributes to 3'-5' DNA helicase activity. Involved in DNA replication and eggshell chorion gene amplification. Located in nucleus. Part of CMG complex and MCM complex. Is expressed in presumptive embryonic/larval central nervous system and unfertilized egg. Orthologous to human MCM6 (minichromosome maintenance complex component 6).
FB Description
Minichromosome maintenance 6 (Mcm6) encodes a subunit of the hetero-hexameric mini-chromosome maintenance (MCM) Complex, which is the eukaryotic replicative DNA helicase. MCM complex requires association with CDC45L and the GINS complex for full helicase activity.