Enables chromatin binding activity. Involved in antimicrobial humoral response; negative regulation of protein export from nucleus; and protein import into nucleus. Located in chromatin; nuclear envelope; and nucleoplasm. Part of nuclear pore. Is expressed in adult head. Human ortholog(s) of this gene implicated in fetal akinesia deformation sequence syndrome 4. Orthologous to human NUP88 (nucleoporin 88).
FB Description
members only (mbo) encodes a nucleoporin involved in immune response transduction by mediating the nuclear translocation of the product of Mad.