Gene

mbo

Species
Drosophila melanogaster
Symbol
mbo
Name
members only
Synonyms
  • 1465/07
  • 1465/7
Biotype
protein coding gene
Automated Description
Enables chromatin binding activity. Involved in antimicrobial humoral response; negative regulation of protein export from nucleus; and protein import into nucleus. Located in chromatin; nuclear envelope; and nucleoplasm. Part of nuclear pore. Is expressed in adult head. Human ortholog(s) of this gene implicated in fetal akinesia deformation sequence syndrome 4. Orthologous to human NUP88 (nucleoporin 88).
FB Description
members only (mbo) encodes a nucleoporin involved in immune response transduction by mediating the nuclear translocation of the product of Mad.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13257
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
12.6765M12.6770M12.6775M12.6780M12.6785M12.6790M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions