Predicted to enable histone binding activity. Predicted to be involved in chromatin remodeling; regulation of transcription by RNA polymerase II; and transcription initiation at RNA polymerase II promoter. Part of super elongation complex. Is expressed in organism. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit) and MLLT3 (MLLT3 super elongation complex subunit).
FB Description
ENL/AF9-related (ear) encodes a transcription factor that is a component of the super elongation complex (SEC), which regulates transcription by RNA Polymerase II. It also interacts with the histone methyltransferase encoded by gpp in the Dot1 complex (DotCom), which modifies chromatin structure by methylating histone H3 on lysine 79.