Gene

LTV1

Species
Drosophila melanogaster
Symbol
LTV1
Name
LTV1 ribosome biogenesis factor
Synonyms
  • BcDNA:LD21529
  • CG7686
Biotype
protein coding gene
Automated Description
Enables ribosome binding activity. Involved in rRNA processing; ribosomal small subunit biogenesis; and ribosomal small subunit export from nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).
FB Description
LTV1 ribosome biogenesis factor (LTV1) encodes a protein involved in pre-rRNA processing that is required for the proper biogenesis of the 40S ribosome. LTV1 product is a direct transcriptional target of Myc, thus it is critical for cell growth and survival.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21531
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
10.8366M10.8368M10.8370M10.8372M10.8374M10.8376M10.8378M10.8380M10.8382M10.8384M10.8386M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions