Gene

Nep2

Species
Drosophila melanogaster
Symbol
Nep2
Name
Neprilysin 2
Synonyms
  • BcDNA:GH07643
  • CG9761
Biotype
protein coding gene
Automated Description
Enables metalloendopeptidase activity. Involved in proteolysis and sperm competition. Located in extracellular space. Is expressed in several structures, including adult brain; epithelium; follicle cell; synaptic neuropil domain; and visceral trunk mesoderm derivative. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Orthologous to human ECEL1 (endothelin converting enzyme like 1).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11733
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
4.720M4.722M4.724M4.726M4.728M4.730M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions