Enables K48-linked polyubiquitin modification-dependent protein binding activity. Involved in positive regulation of compound eye retinal cell apoptotic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including head; ovary; and pigment cell.
FB Description
modifier of rpr and grim, ubiquitously expressed (morgue) encodes an F box/ubiquitin conjugase domain protein. It regulates cell death by controlling the levels of the apoptosis inhibitor encoded by Diap1.