Predicted to enable protein-macromolecule adaptor activity and signaling receptor binding activity. Involved in apposition of dorsal and ventral imaginal disc-derived wing surfaces; cell-matrix adhesion; and muscle attachment. Located in focal adhesion. Is expressed in several structures, including adult CNS glial cell; adult head; adult heart; germ layer; and muscle cell. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ILK (integrin linked kinase).
FB Description
Integrin linked kinase (Ilk) encodes a pseudokinase that, together with the products of stck and parvin, mediates part of the adhesive functions of integrins.