Gene

Ilk

Species
Drosophila melanogaster
Symbol
Ilk
Name
Integrin linked kinase
Synonyms
  • CG10504
  • CT29478
Biotype
protein coding gene
Automated Description
Predicted to enable protein-macromolecule adaptor activity and signaling receptor binding activity. Involved in apposition of dorsal and ventral imaginal disc-derived wing surfaces; cell-matrix adhesion; and muscle attachment. Located in focal adhesion. Is expressed in several structures, including adult CNS glial cell; adult head; adult heart; germ layer; and muscle cell. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ILK (integrin linked kinase).
FB Description
Integrin linked kinase (Ilk) encodes a pseudokinase that, together with the products of stck and parvin, mediates part of the adhesive functions of integrins.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44329
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
21.2170M21.2172M21.2174M21.2176M21.2178M21.2180M21.2182M21.2184M21.2186M21.2188M21.2190M21.2192M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions