Gene

EndoGI

Species
Drosophila melanogaster
Symbol
EndoGI
Name
Endonuclease G inhibitor
Synonyms
  • BG:DS07473.2
  • CG4930
Biotype
protein coding gene
Automated Description
Enables ribonuclease inhibitor activity. Involved in positive regulation of Notch signaling pathway. Located in nucleus. Is expressed in several structures, including adult head; cuboidal/columnar epithelium; embryonic/larval salivary gland; ganglia; and nurse cell.
FB Description
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12604
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
16.2578M16.2580M16.2582M16.2584M16.2586M16.2588M16.2590M16.2592M16.2594M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions