Enables ribonuclease inhibitor activity. Involved in positive regulation of Notch signaling pathway. Located in nucleus. Is expressed in several structures, including adult head; cuboidal/columnar epithelium; embryonic/larval salivary gland; ganglia; and nurse cell.
FB Description
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme.