Gene

AdamTS-B

Species
Drosophila melanogaster
Symbol
AdamTS-B
Name
ADAM metallopeptidase with thrombospondin type 1 motif B
Synonyms
  • AdamTS-B
  • CG4096
Biotype
protein coding gene
Automated Description
Predicted to enable metalloendopeptidase activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway and negative regulation of imaginal disc-derived wing vein specification. Predicted to be active in extracellular matrix. Is expressed in several structures, including clypeo-labral primordium; dorsal epidermis primordium; embryonic epipharynx; embryonic hypopharynx; and presumptive wing vein. Human ortholog(s) of this gene implicated in Weill-Marchesani syndrome and congenital heart disease. Orthologous to several human genes including ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) and ADAMTS7 (ADAM metallopeptidase with thrombospondin type 1 motif 7).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13723
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.699M5.700M5.701M5.702M5.703M5.704M5.705M5.706M5.707M5.708M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions