Gene

Bcat

Species
Drosophila melanogaster
Symbol
Bcat
Name
Branched chain amino acid transaminase
Synonyms
  • bcat
  • BCAT
Biotype
protein coding gene
Automated Description
Enables L-isoleucine-2-oxoglutarate transaminase activity; L-leucine-2-oxoglutarate transaminase activity; and L-valine-2-oxoglutarate transaminase activity. Involved in L-leucine catabolic process; isoleucine catabolic process; and valine catabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in adult head and spermatozoon. Used to study amino acid metabolic disorder. Human ortholog(s) of this gene implicated in hypervalinemia and hyperleucine-isoleucinemia. Orthologous to several human genes including BCAT2 (branched chain amino acid transaminase 2).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11825
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
13.3970M13.3975M13.3980M13.3985M13.3990M13.3995M13.4000M13.4005M13.4010M

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

2 interactor genes based on 2 annotations
Bcat molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
CthDrosophila melanogaster
protein
  • two hybrid array
PMID:19079254
protein
Lipt1Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
Showing 1 - 2 of 2 rows
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Genetic Interactions