Gene

Ndc80

Species
Drosophila melanogaster
Symbol
Ndc80
Name
Ndc80
Synonyms
  • CG9938
  • dmNdc80
Biotype
protein coding gene
Automated Description
Involved in mitotic metaphase chromosome alignment. Located in kinetochore. Part of Ndc80 complex. Is expressed in adult heart and organism. Orthologous to human NDC80 (NDC80 kinetochore complex component).
FB Description
Ndc80 (Ndc80) encodes a protein involved in mitotic metaphase plate congression.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10643
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensNDC805 of 9YesYes   
Mus musculusNdc806 of 9YesYes   
Rattus norvegicusNdc805 of 9YesYes   
Xenopus tropicalisndc805 of 9YesYes   
Danio reriondc804 of 10YesYes  
Caenorhabditis elegansndc-805 of 9YesYes   
Saccharomyces cerevisiaeNDC803 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
13.6098M13.6100M13.6102M13.6104M13.6106M13.6108M13.6110M13.6112M13.6114M13.6116M13.6118M13.6120M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
Ndc80Dendra2
  • Ndc80[Dendra2]
allele
NC_004354.4:g.13610084G>T
    variant
    SNP
    • missense variant
    NC_004354.4:g.13610343A>T
      variant
      SNP
      • missense variant
      NC_004354.4:g.13610424G>A
        variant
        SNP
        • missense variant
        NC_004354.4:g.13611270T>C
          variant
          SNP
          • intron variant
          NC_004354.4:g.13610106G>A
            variant
            SNP
            • missense variant
            NC_004354.4:g.13610765G>C
              variant
              SNP
              • missense variant
              NC_004354.4:g.13610781C>A
                variant
                SNP
                • missense variant
                NC_004354.4:g.13609989G>A
                  variant
                  SNP
                  • missense variant
                  NC_004354.4:g.13610091C>A
                    variant
                    Showing 1 - 10 of 74 rows
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                    Transgenic Alleles

                    Species
                    (carrying the transgene)
                    Allele symbol
                    Transgenic construct
                    Expressed components
                    Knock-down targets
                    Regulatory regions
                    Has Disease Annotations
                    Has Phenotype Annotations
                    Drosophila melanogasterNdc80EGFP
                      Drosophila melanogasterNdc80GD14729
                        • UASt
                        Drosophila melanogasterNdc80GL00625
                          • UAS
                          Drosophila melanogasterNdc80HMS01704
                            • UAS
                            Drosophila melanogasterNdc80NIG.9938R
                              • UASt
                              Drosophila melanogasterNdc80UAS.EGFP
                                • UASt
                                Drosophila melanogasterNdc80UAS.ORF.Tag:HA
                                  • UASt
                                  Drosophila melanogasterNdc80UAS.ORF
                                    • UASt
                                    Drosophila melanogasterNdc80mRFP1
                                      Showing 1 - 9 of 9 rows
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                                      Models

                                      No data available

                                      Sequence Feature Viewer

                                      Genome location
                                      Assembly version
                                      R6
                                      Viewer Help
                                      13.6098M13.6100M13.6102M13.6104M13.6106M13.6108M13.6110M13.6112M13.6114M13.6116M13.6118M13.6120MNdc80-RA (Ndc80)

                                      Sequence Details

                                      Loading...

                                      Expression

                                      Primary Sources
                                      Other Sources
                                      Must provide at least one subject
                                      Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

                                      Molecular Interactions

                                      39 interactor genes based on 56 annotations
                                      Ndc80 molecule type
                                      Interactor gene
                                      Interactor species
                                      Interactor molecule type
                                      Detection methods
                                      Source
                                      Reference
                                      protein
                                      btvDrosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:17534428
                                      protein
                                      Cenp-CDrosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:21353555
                                      protein
                                      CG3339Drosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:17534428
                                      protein
                                      CG5376Drosophila melanogaster
                                      protein
                                      • two hybrid
                                      PMID:14605208
                                      protein
                                      CG7611Drosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:17534428
                                      protein
                                      CG12470Drosophila melanogaster
                                      protein
                                      • two hybrid
                                      PMID:14605208
                                      protein
                                      CG14868Drosophila melanogaster
                                      protein
                                      • two hybrid
                                      PMID:14605208
                                      protein
                                      cmetDrosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:17534428
                                      protein
                                      cpaDrosophila melanogaster
                                      protein
                                      • anti tag coimmunoprecipitation
                                      PMID:17534428
                                      protein
                                      CSN4Drosophila melanogaster
                                      protein
                                      • two hybrid
                                      PMID:14605208
                                      Showing 1 - 10 of 55 rows
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                                      Genetic Interactions

                                      Ndc80 role
                                      Ndc80 genetic perturbation
                                      Interactor gene
                                      Interactor species
                                      Interactor role
                                      Interactor genetic perturbation
                                      Interaction type
                                      Phenotype or trait
                                      Source
                                      Reference
                                      enhancer gene
                                      cmetDrosophila melanogaster
                                      enhanced gene
                                      genetic enhancement
                                        PMID:26473960
                                        Showing 1 - 1 of 1 rows
                                        per page