Enables cysteine-type endopeptidase activity. Involved in proteolysis. Located in perivitelline space. Is expressed in several structures, including adult brain cell body rind; adult head; adult heart; apoptotic amnioserosa; and ganglia. Human ortholog(s) of this gene implicated in diabetes mellitus. Orthologous to human CTSB (cathepsin B).
FB Description
Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation.