Gene

CG5445

Species
Drosophila melanogaster
Symbol
CG5445
Name
Not Available
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin binding activity. Predicted to be involved in macroautophagy. Predicted to be active in phagophore assembly site. Is expressed in organism. Orthologous to human ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20930
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensILRUN7 of 9YesYes   
Mus musculusIlrun7 of 9YesYes   
Rattus norvegicusIlrun7 of 9YesYes   
Danio rerioilrun7 of 10YesYes  
Caenorhabditis elegansC36E6.24 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
fertile
viable
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
17.284M17.286M17.288M17.290M17.292M17.294M17.296M17.298M17.300M17.302M17.304M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
CG544569
  • CG5445[69]
  • Suppressor[#69]
allele
CG5445e00540
  • CG5445[e00540]
allele
CG5445GG01305
  • CG5445[GG01305]
allele
CG5445c06921
  • CG5445[c06921]
allele
CG5445e00593
  • CG5445[e00593]
allele
Yes
CG5445CR71181-TG4.2
  • CG5445[CR71181-TG4.2]
allele
CG5445NP1076
  • CG5445[NP1076]
allele
CG5445G1722
  • CG5445[G1722]
allele with one associated variant
insertion
  • intron variant
CG5445G389
  • CG5445[G389]
allele with one associated variant
insertion
  • intron variant
CG5445G703
  • CG5445[G703]
allele with one associated variant
insertion
  • intron variant
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterCG5445HMJ23222
  • UAS
Drosophila melanogasterCG5445KK107320
  • UASt
Drosophila melanogasterCG5445NIG.5445R
  • UASt
Drosophila melanogasterCG5445UAS.cUa
  • UAS
Drosophila melanogasterCG5445ΔFW.UAS
  • UAS
Drosophila melanogasterCG5445ΔUBA.UAS
  • UAS
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
17.284M17.286M17.288M17.290M17.292M17.294M17.296M17.298M17.300M17.302M17.304MCG5445-RA (CG5445)CG5445-RB (CG5445)CG5445-RD (CG5445)CG5445-RF (CG5445)CG5445-RG (CG5445)CG8664-RA (CG8664)CG8664-RB (CG8664)CG8661-RA (CG8661)Fim-RA (Fim)Fim-RC (Fim)Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

18 interactor genes based on 20 annotations
CG5445 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
awdDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG4306Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG7856Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG8993Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG8993Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:38944040
protein
CG9173Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG9784Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG15308Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG34396Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Cp36Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
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Genetic Interactions

CG5445 role
CG5445 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
suppressor gene
TxlDrosophila melanogaster
suppressed gene
genetic suppression
    PMID:29109084
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