Gene

Nse1

Species
Drosophila melanogaster
Symbol
Nse1
Name
Non-SMC element 1
Synonyms
  • anon-WO0118547.82
  • CG11329
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein ubiquitination. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component).
FB Description
Non-SMC element 1 (Nse1) encodes a RING finger protein with E3 ubiquitin ligase activity that is part of the SMC5/6 protein complex. This complex is critical to genome stability, and is required for homologous DNA recombination-based processes.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20973
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.6767M6.6768M6.6769M6.6770M6.6771M6.6772M6.6773M6.6774M6.6775M6.6776M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions