Gene

Aatf

Species
Drosophila melanogaster
Symbol
Aatf
Name
Apoptosis antagonizing transcription factor
Synonyms
  • AATF
  • anon-WO0118547.190
Biotype
protein coding gene
Automated Description
Involved in negative regulation of programmed cell death and oogenesis. Located in nucleolus. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; and larval muscle cell. Used to study chromosome 17q12 deletion syndrome. Orthologous to human AATF (apoptosis antagonizing transcription factor).
FB Description
Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15565
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.7178M6.7180M6.7182M6.7184M6.7186M6.7188M6.7190M6.7192M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions