Gene

Pvf2

Species
Drosophila melanogaster
Symbol
Pvf2
Name
PDGF- and VEGF-related factor 2
Synonyms
  • CG13780
  • DmVEGF-2
Biotype
protein coding gene
Automated Description
Enables chemoattractant activity. Involved in several processes, including hemocyte migration; hemocyte proliferation; and positive regulation of cell size. Acts upstream of with a positive effect on neuron remodeling. Is active in extracellular space. Is expressed in several structures, including Malpighian tubule; Malpighian tubule primordium; cardiogenic mesoderm; gut section; and intestinal stem cell.
FB Description
PDGF- and VEGF-related factor 2 (Pvf2) encodes a ligand for the receptor tyrosine kinase enocded by Pvr. It has roles in embryonic plasmatocyte survival and migration, and in the proliferation of adult midgut intestinal stem cells.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21719
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

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        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Pvf2 molecule type
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              Genetic Interactions

              Pvf2 role
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