Enables G protein-coupled receptor binding activity and diuretic hormone activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of feeding behavior; and positive regulation of circadian sleep/wake cycle, wakefulness. Acts upstream of with a positive effect on courtship behavior. Located in cytoplasm and extracellular space. Is expressed in several structures, including adult gnathal ganglion; epithelial cell; gut section; synaptic neuropil domain; and synaptic neuropil subdomain.
FB Description
Diuretic hormone 31 (Dh31) encodes a neuropeptide which regulates fluid secretion and controls the switch between feeding and courtship behaviour. Dh31 levels increase following the consumption of protein-rich food. In the brain Dh31 excites two distinct populations of neurons, responsible for two parallel pathways, one inhibiting feeding through AstC and the other promoting courtship through Crz.