Gene

Nedd8

Species
Drosophila melanogaster
Symbol
Nedd8
Name
Nedd8 ubiquitin like modifier
Synonyms
  • CG10679
  • dNEDD8
Biotype
protein coding gene
Automated Description
Enables protein tag activity. Involved in several processes, including female germ-line stem cell population maintenance; negative regulation of smoothened signaling pathway; and protein neddylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human NEDD8 (NEDD8 ubiquitin like modifier).
FB Description
Nedd8 (Nedd8) encodes a ubiquitin-like polypeptide involved in protein ubiquitination and degradation, via Cullin neddylation. Nedd8-mediated modification has been implicated in signal transduction, cell proliferation and differentiation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10666
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.9511M18.9512M18.9513M18.9514M18.9515M18.9516M18.9517M18.9518M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions