Enables protein tag activity. Involved in several processes, including female germ-line stem cell population maintenance; negative regulation of smoothened signaling pathway; and protein neddylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human NEDD8 (NEDD8 ubiquitin like modifier).
FB Description
Nedd8 (Nedd8) encodes a ubiquitin-like polypeptide involved in protein ubiquitination and degradation, via Cullin neddylation. Nedd8-mediated modification has been implicated in signal transduction, cell proliferation and differentiation.