Version: 8.0.0
Date: Tue Jan 28 2025
Or42b
Drosophila melanogasterFB:FBgn0033043
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Or42b

Species
Drosophila melanogaster
Symbol
Or42b
Name
Odorant receptor 42b
Synonyms
  • 41E.1
  • 42b
Biotype
protein coding gene
Automated Description
Enables olfactory receptor activity. Involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be part of cation channel complex. Predicted to be active in plasma membrane. Is expressed in adult olfactory receptor neuron Or42b; antennal basiconic sensillum ab1; antennal lobe glomerulus DM1; larval antennal lobe glomerulus 42b; and larval olfactory receptor neuron Or42b.
FB Description
Odorant receptor 42b (Or42b) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21137
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            5.7972M5.7974M5.7976M5.7978M5.7980M5.7982M5.7984M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Or42b molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Or42b role
              Or42b genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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