Gene

Corin

Species
Drosophila melanogaster
Symbol
Corin
Name
Corin
Synonyms
  • CG2105
  • corin
Biotype
protein coding gene
Automated Description
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy; hypertension; and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24253
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCORIN3 of 9YesYes   
Mus musculusCorin4 of 9YesYes   
Rattus norvegicusCorin4 of 9YesYes   
Xenopus tropicaliscorin3 of 9YesYes   
Xenopus tropicalisxepsin2 of 9YesYes   
Danio reriocorin3 of 10YesYes  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
flz1177732202 of 8  
CG81702109733222 of 8  
Np3105434212 of 8  
CG1299440944282 of 8  
CG13744537145302 of 8  
Sb637146282 of 8  
CG8172727156372 of 8  
CG6462835942282 of 8  
CG6048927449332 of 8  
CG327551026449332 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
7.542M7.544M7.546M7.548M7.550M7.552M7.554M7.556M7.558M7.560M7.562M7.564M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
CorinCR01512-TG4.0
  • Corin[CR01512-TG4.0]
allele
CorinMI13299
  • Corin[MI13299]
allele with one associated variant
insertion
  • 3 prime UTR variant
CorinMI06958
  • Corin[MI06958]
allele with one associated variant
insertion
  • intron variant
CorinMB02295
  • Corin[MB02295]
allele with one associated variant
insertion
  • intron variant
NT_033778.4:g.7541621G>Cvariant
SNP
  • intron variant
NT_033778.4:g.7541790G>Avariant
SNP
  • intron variant
NT_033778.4:g.7545801G>Avariant
SNP
  • 5 prime UTR variant
NT_033778.4:g.7546884G>Cvariant
SNP
  • intron variant
NT_033778.4:g.7548742T>Cvariant
SNP
  • intron variant
NT_033778.4:g.7549012G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 558 rows
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterCorinGD1850
  • UASt
Drosophila melanogasterCorinGL01216
  • UAS
Drosophila melanogasterCorinHMS02287
  • UAS
Drosophila melanogasterCorinKK108495
  • UASt
Drosophila melanogasterCorinNIG.2105R
  • UASt
Drosophila melanogasterCorinU6.NIG.sgRNA
Showing 1 - 6 of 6 rows
per page

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.542M7.544M7.546M7.548M7.550M7.552M7.554M7.556M7.558M7.560M7.562M7.564MCorin-RB (Corin)Corin-RC (Corin)Rpe-RA (Rpe)Rpe-RB (Rpe)

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Corin molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
RNA
bratDrosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:26527002
Showing 1 - 1 of 1 rows
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Genetic Interactions

No data available