Gene

Gnptab

Species
Drosophila melanogaster
Symbol
Gnptab
Name
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Synonyms
  • CG8027
  • Cg8027
Biotype
protein coding gene
Automated Description
Predicted to enable UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity. Predicted to be involved in N-glycan processing to lysosome. Predicted to be active in Golgi membrane. Is expressed in organism. Human ortholog(s) of this gene implicated in mucolipidosis II alpha/beta and mucolipidosis III alpha/beta. Orthologous to human GNPTAB (N-acetylglucosamine-1-phosphate transferase subunits alpha and beta).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24045
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensGNPTAB8 of 9YesYes   
Mus musculusGnptab8 of 9YesYes   
Rattus norvegicusGnptab8 of 9YesYes   
Danio reriognptab8 of 10YesYes  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
Gnptab (Dme)
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
9.2045M9.2050M9.2055M9.2060M9.2065M9.2070M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
GnptabCR70008-KO-kG4
  • Gnptab[CR70008-KO-kG4]
allele
NT_033778.4:g.9204692C>Avariant
SNP
  • 3 prime UTR variant
NT_033778.4:g.9205406G>Tvariant
SNP
  • intron variant
NT_033778.4:g.9205017C>Tvariant
SNP
  • missense variant
NT_033778.4:g.9204632A>Gvariant
SNP
  • 3 prime UTR variant
NT_033778.4:g.9204761A>Gvariant
SNP
  • 3 prime UTR variant
NT_033778.4:g.9205398A>Gvariant
SNP
  • splice region variant
NT_033778.4:g.9205935A>Gvariant
SNP
  • missense variant
NT_033778.4:g.9206704T>Gvariant
SNP
  • missense variant
NT_033778.4:g.9204734T>Cvariant
SNP
  • 3 prime UTR variant
Showing 1 - 10 of 57 rows
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterGnptabGD1895
  • UASt
Drosophila melanogasterGnptabHMJ23072
  • UAS
Drosophila melanogasterGnptabKK100171
  • UASt
Drosophila melanogasterGnptabNIG.8027R
  • UASt
Drosophila melanogasterGnptabU6.NIG.sgRNA
Showing 1 - 5 of 5 rows
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
9.2045M9.2050M9.2055M9.2060M9.2065M9.2070MGnptab-RA (Gnptab)

Sequence Details

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Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
Gnptab (Dme)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Gnptab molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
CG4367Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
Showing 1 - 1 of 1 rows
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Genetic Interactions

No data available