Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of DNA-templated transcription and spermatogenesis. Located in nucleus. Is expressed in several structures, including antennal anlage; ganglia; gonad; head epidermis primordium; and male germline cell. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1) and TGIF2 (TGFB induced factor homeobox 2).
FB Description
achintya (achi) encodes a homeodomain transcription factor (TGIF subclass) that is required along with homeodomain protein encoded by vis for meiotic division in spermatogenesis.