Gene

Mtap

Species
Drosophila melanogaster
Symbol
Mtap
Name
Methylthioadenosine phosphorylase
Synonyms
  • CG4802
  • Methylthioadenosine phosphorylase ortholog
Biotype
protein coding gene
Automated Description
Predicted to enable S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be active in cytosol. Is expressed in adult head; fat body primordium; and visceral trunk mesoderm. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine phosphorylase).
FB Description
Methylthioadenosine phosphorylase (Mtap) encodes an enzyme that plays a key role in the methionine salvage pathway and in the production of endogenous cellular adenine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR42679
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
17.4278M17.4280M17.4282M17.4284M17.4286M17.4288M17.4290M17.4292M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions