Predicted to enable S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be active in cytosol. Is expressed in adult head; fat body primordium; and visceral trunk mesoderm. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine phosphorylase).
FB Description
Methylthioadenosine phosphorylase (Mtap) encodes an enzyme that plays a key role in the methionine salvage pathway and in the production of endogenous cellular adenine.