Gene

P32

Species
Drosophila melanogaster
Symbol
P32
Name
P32
Synonyms
  • CG 6459
  • CG6459
Biotype
protein coding gene
Automated Description
Enables histone binding activity. Involved in nucleosome assembly and sperm DNA decondensation. Located in mitochondrion and nucleus. Is expressed in several structures, including embryonic/larval midgut primordium; epithelial tube; gut section; head; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein).
FB Description
P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10826
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
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    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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          Experimental condition
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          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            17.6714M17.6716M17.6718M17.6720M17.6722M17.6724M17.6726M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            P32 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              P32 role
              P32 genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
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              Phenotype or trait
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