Enables serine hydrolase activity. Predicted to be involved in epoxide metabolic process and juvenile hormone catabolic process. Is expressed in several structures, including adult head; adult heart; embryonic proventriculus inner layer; embryonic/larval oenocyte; and gut section. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1).
FB Description
Juvenile hormone epoxide hydrolase 2 (Jheh2) encodes an enzyme that hydrolyzes cis-stilbene oxide. Jheh2 expression changes are associated with increased tolerance to oxidative stress.