Gene

Jheh2

Species
Drosophila melanogaster
Symbol
Jheh2
Name
Juvenile hormone epoxide hydrolase 2
Synonyms
  • CG15102
  • CT34977
Biotype
protein coding gene
Automated Description
Enables serine hydrolase activity. Predicted to be involved in epoxide metabolic process and juvenile hormone catabolic process. Is expressed in several structures, including adult head; adult heart; embryonic proventriculus inner layer; embryonic/larval oenocyte; and gut section. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1).
FB Description
Juvenile hormone epoxide hydrolase 2 (Jheh2) encodes an enzyme that hydrolyzes cis-stilbene oxide. Jheh2 expression changes are associated with increased tolerance to oxidative stress.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21661
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.8558M18.8560M18.8562M18.8564M18.8566M18.8568M18.8570M18.8572M18.8574M18.8576M18.8578M18.8580M18.8582M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions