Version: 8.0.0
Date: Tue Jan 28 2025
Magi
Drosophila melanogasterFB:FBgn0034590
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Magi

Species
Drosophila melanogaster
Symbol
Magi
Name
Magi
Synonyms
  • CG15656
  • CG30388
Biotype
protein coding gene
Automated Description
Enables small GTPase binding activity. Involved in adherens junction organization. Located in several cellular components, including adherens junction; apicolateral plasma membrane; and muscle cell postsynaptic specialization. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in nephrotic syndrome type 15. Orthologous to several human genes including MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3).
FB Description
Magi (Magi) encodes a molecular scaffolding protein that is involved in adherens junction (AJ) organization. Magi is ubiquitously expressed and its product localizes at AJ with the Par polarity complex.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10316
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
            Viewer Help
            21.130M21.132M21.134M21.136M21.138M21.140M21.142M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Magi molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Magi role
              Magi genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
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