Gene

YME1L

Species
Drosophila melanogaster
Symbol
YME1L
Name
YME1 like ATPase
Synonyms
  • CG3499
  • DmCG3499
Biotype
protein coding gene
Automated Description
Predicted to enable ATP-dependent peptidase activity and metalloendopeptidase activity. Predicted to be involved in mitochondrial protein catabolic process and mitochondrial protein processing. Located in mitochondrion. Is expressed in several structures, including adult head; embryonic anal pad; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase).
FB Description
YME1 like ATPase (YME1L) encodes an AAA protease localized at the mitochondrial inner membrane. It is involved in mitochondrial quality control and its loss causes male sterility, premature aging, and neuromuscular degenerative phenotypes.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43655
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
22.8830M22.8835M22.8840M22.8845M22.8850M22.8855M22.8860M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions