Version: 8.0.0
Date: Tue Jan 28 2025
RhoGEF64C
Drosophila melanogasterFB:FBgn0035574
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

RhoGEF64C

Species
Drosophila melanogaster
Symbol
RhoGEF64C
Name
Rho guanine nucleotide exchange factor at 64C
Synonyms
  • CG13709
  • CG13710
Biotype
protein coding gene
Automated Description
Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including imaginal disc-derived leg morphogenesis; positive regulation of Rho protein signal transduction; and spiracle morphogenesis, open tracheal system. Located in apical cortex. Is expressed in several structures, including Malpighian tubule tip cell primordium; centripetal follicle cell; embryonic Malpighian tubule tip cell; epithelium; and gut section.
FB Description
Rho guanine nucleotide exchange factor at 64C (RhoGEF64C) encodes a guanine nucleotide exchange factor with apical protein localization. In some ectodermal cells localization is controlled at the level of RNA.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46006
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
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Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
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      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            Data currently unavailable; sequence viewer under construction

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            RhoGEF64C molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              RhoGEF64C role
              RhoGEF64C genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
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