Gene

Aps

Species
Drosophila melanogaster
Symbol
Aps
Name
Aps pyrophosphatase
Synonyms
  • anon-WO0118547.266
  • Aps
Biotype
protein coding gene
Automated Description
Enables bis(5'-adenosyl)-hexaphosphatase activity and inositol diphosphate pentakisphosphate diphosphatase activity. Involved in several processes, including glucose homeostasis; inositol phosphate metabolic process; and lipid homeostasis. Located in cytoplasm and nucleus. Is expressed in several structures, including central brain primordium; embryonic brain; embryonic central brain neurons; embryonic/larval midgut primordium; and gut section. Orthologous to several human genes including NUDT4 (nudix hydrolase 4) and NUDT4B (nudix hydrolase 4B).
FB Description
Aps (Aps) encodes a diphosphoinositol-polyphosphate diphosphatase that hydrolyses a range of (di)nucleoside polyphosphates. It is involved in glucose and lipid homeostasis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12629
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
10.8950M10.8955M10.8960M10.8965M10.8970M10.8975M10.8980M10.8985M10.8990M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions