Gene

Pop2

Species
Drosophila melanogaster
Symbol
Pop2
Name
Pop2
Synonyms
  • Caf1
  • CAF1
Biotype
protein coding gene
Automated Description
Enables poly(A)-specific ribonuclease activity. Involved in negative regulation of translation and nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Part of CCR4-NOT complex. Is expressed in several structures, including adult brain cell body rind; adult head; embryonic/larval midgut primordium; ganglia; and head epidermis primordium. Used to study heart disease. Orthologous to several human genes including CNOT7 (CCR4-NOT transcription complex subunit 7).
FB Description
Pop2 (Pop2) encodes a poly(A)-specific ribonuclease involved in translation inhibition.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10797
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
11.9985M11.9990M11.9995M12.0000M12.0005M12.0010M12.0015M12.0020M12.0025M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions