Enables poly(A)-specific ribonuclease activity. Involved in negative regulation of translation and nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Part of CCR4-NOT complex. Is expressed in several structures, including adult brain cell body rind; adult head; embryonic/larval midgut primordium; ganglia; and head epidermis primordium. Used to study heart disease. Orthologous to several human genes including CNOT7 (CCR4-NOT transcription complex subunit 7).
FB Description
Pop2 (Pop2) encodes a poly(A)-specific ribonuclease involved in translation inhibition.