Involved in several processes, including genitalia development; regulation of alternative mRNA splicing, via spliceosome; and somatic sex determination. Located in nucleus. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including accessory medulla; brain; embryonic hemocyte primordium; gut section; and imaginal disc. Orthologous to human SRRM1 (serine and arginine repetitive matrix 1).
FB Description
SRm160 (SRm160) encodes a conserved RNA-binding protein that participates in the exon junction complex and is involved in pre-mRNA splicing and 3' end formation. It participates in somatic sex determination, cell death, retinal development and the control of circadian rhythm. Direct targets include rl.