Version: 8.0.0
Date: Tue Jan 28 2025
Gbs-70E
Drosophila melanogasterFB:FBgn0036428
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Gbs-70E

Species
Drosophila melanogaster
Symbol
Gbs-70E
Name
Glycogen binding subunit 70E
Synonyms
  • anon-WO0118547.400
  • CG9238
Biotype
protein coding gene
Automated Description
Enables glycogen binding activity and protein phosphatase 1 binding activity. Involved in behavioral response to ethanol and regulation of glycogen metabolic process. Part of protein phosphatase type 1 complex. Is expressed in several structures, including anlage in statu nascendi; embryonic/larval midgut primordium; endoderm anlage; gut section; and head epidermis primordium. Used to study alcohol use disorder. Orthologous to human PPP1R3B (protein phosphatase 1 regulatory subunit 3B) and PPP1R3C (protein phosphatase 1 regulatory subunit 3C).
FB Description
Glycogen binding subunit 70E (Gbs-70E) is one of the glycogen binding subunits of protein phosphatase 1 (Pp1) that interacts with all of the known Pp1 catalytic subunits (encoded by Pp1-87B, flw, Pp1alpha-96A, and Pp1-13C). The product of Gbs-70E is involved in the regulation of glycogen metabolism, and plays a role in the egg development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12307
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
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    Variant
    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

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        Experimental condition
        Associated Human Diseases
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Gbs-70E molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
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            Genetic Interactions

            Gbs-70E role
            Gbs-70E genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
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