Gene

Chmp1

Species
Drosophila melanogaster
Symbol
Chmp1
Name
Charged multivesicular body protein 1
Synonyms
  • CG4108
  • CHMP1
Biotype
protein coding gene
Automated Description
Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Located in apical part of cell and late endosome. Is expressed in adult head. Orthologous to human CHMP1B (charged multivesicular body protein 1B).
FB Description
Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10476
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.6830M18.6832M18.6834M18.6836M18.6838M18.6840M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions