Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Located in apical part of cell and late endosome. Is expressed in adult head. Orthologous to human CHMP1B (charged multivesicular body protein 1B).
FB Description
Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.