Predicted to enable Rho GDP-dissociation inhibitor activity. Predicted to be involved in Rho protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol and membrane. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; dorsal pharyngeal muscle primordium; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Orthologous to human ARHGDIA (Rho GDP dissociation inhibitor alpha); ARHGDIB (Rho GDP dissociation inhibitor beta); and ARHGDIG (Rho GDP dissociation inhibitor gamma).