Involved in sexual reproduction. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen); HMSD (histocompatibility minor serpin domain containing); and SERPINH1 (serpin family H member 1).