Involved in rRNA 2'-O-methylation. Located in nucleolus. Is expressed in several structures, including adult head; antennal primordium; embryonic/larval midgut primordium; head epidermis primordium; and larval muscle cell. Orthologous to human NOLC1 (nucleolar and coiled-body phosphoprotein 1).
FB Description
Nopp140 (Nopp140) encodes a nucleolar and Cajal body protein. It is predicted to function as a chaperone in the assembly of small nucleolar ribonucleoprotein particles within Cajal bodies, their transit to nucleoli, and their association with pre-ribosomal RNA within nucleolar dense fibrillar regions.