Gene

ArfGAP3

Species
Drosophila melanogaster
Symbol
ArfGAP3
Name
ADP-ribosylation factor GTPase activating protein 3
Synonyms
  • AG2
  • arfgap1
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase activator activity. Involved in compound eye morphogenesis. Located in cytoplasm. Colocalizes with adherens junction. Is expressed in several structures, including adult head; anlage in statu nascendi; embryonic/larval midgut; gland; and salivary gland body primordium. Orthologous to several human genes including ARFGAP2 (ARF GTPase activating protein 2).
FB Description
ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45686
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
22.7145M22.7150M22.7155M22.7160M22.7165M22.7170M22.7175M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions