Gene

Hat1

Species
Drosophila melanogaster
Symbol
Hat1
Name
Histone acetyltransferase 1
Synonyms
  • CG2051
  • dmHAG409
Biotype
protein coding gene
Automated Description
Enables histone H4 acetyltransferase activity. Involved in CENP-A containing chromatin assembly. Predicted to be located in nucleus. Is expressed in dorsal epidermis primordium; embryonic dorsal epidermis; embryonic ventral epidermis; gut section; and ventral epidermis primordium. Orthologous to human HAT1 (histone acetyltransferase 1).
FB Description
Histone acetyltransferase 1 (Hat1) encodes a B-type histone acetyltransferase that localizes to both the cytoplasm and the nucleus. It is involved in the escort machinery of newly synthesized histones encoded by His3 and His4 to chromatin and acetylates the product of His4 at lysines 5 and 12. It also forms a complex with centromeric histone encoded by cid and is involved in cid chromatin assembly.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12046
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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5.7874M5.7876M5.7878M5.7880M5.7882M5.7884M5.7886M5.7888M5.7890M5.7892M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions