Enables histone H4 acetyltransferase activity. Involved in CENP-A containing chromatin assembly. Predicted to be located in nucleus. Is expressed in dorsal epidermis primordium; embryonic dorsal epidermis; embryonic ventral epidermis; gut section; and ventral epidermis primordium. Orthologous to human HAT1 (histone acetyltransferase 1).
FB Description
Histone acetyltransferase 1 (Hat1) encodes a B-type histone acetyltransferase that localizes to both the cytoplasm and the nucleus. It is involved in the escort machinery of newly synthesized histones encoded by His3 and His4 to chromatin and acetylates the product of His4 at lysines 5 and 12. It also forms a complex with centromeric histone encoded by cid and is involved in cid chromatin assembly.