Gene

Snx3

Species
Drosophila melanogaster
Symbol
Snx3
Name
Sorting nexin 3
Synonyms
  • CG6359
  • DmSNX3
Biotype
protein coding gene
Automated Description
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in endocytic recycling; protein stabilization; and wing disc development. Located in early endosome. Part of retromer complex. Is expressed in adult head and adult heart. Orthologous to several human genes including SNX12 (sorting nexin 12).
FB Description
Sorting nexin 3 (Snx3) encodes a protein involved in the secretion of the morphogen encoded by wg. It regulates the retromer-dependent recycling of the transmembrane cargo encoded by wls.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45963
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            12.6282M12.6284M12.6286M12.6288M12.6290M12.6292M12.6294M12.6296M12.6298M12.6300M12.6302M12.6304M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Snx3 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              Snx3 role
              Snx3 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
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